A.I. BURNASYAN FMBC CLINICAL BULLETIN

ISSN 2782-6430 (print)

State Research Center −Burnasyan Federal Medical Biophysical
Center of Federal Medical Biological Agency

The journal is published in Russian.
Format – A4.
The periodicity of the journal is 4 times a year.

Issue №2 2025 год

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A.I. Burnasyan  FMBC clinical bulletin. 2024 № 4

I.V. Tsymbal ¹, M.S. Semenov ¹, V.A. Brunchukov ¹, E.A. Dubova ¹, G.G. Stepanyan ¹, L.T. Lepsveridze ¹, S.V. Lischuk ¹,
T.A. Astrelina ¹, I.V. Kobzeva ¹, Yu.B. Suchkova ¹, O.F. Serova ², A.S. Samoilov ¹, O.V. Parinov 1,2

 The Usage of an Amniotic Membrane to Minimize Pathological Scarring 
 in Nerve Neurotization Surgery

1International Office, State Research Center – Burnasyan Federal Medical Biophysical Center  of Federal Medical Biological Agency, Moscow, Russiа

2Moscow regional Perinatal Center, Russia, Moscow region, Balashikha

Contact person:Semenov Maxim: semenovfmbc@gmail.com

Abstract
Despite modern advances in surgery, the problem of pathological scarring is still remains relevant. It can lead to both serious dysfunctions of various organ systems and cosmetic defects, which significantly reduces the quality of patients’ life. In search of effective methods for the prevention of scarring, we paid attention to the amniotic sac, which, due to its properties, is able to provide tissue protection and prevent scar-adhesive processes. We have illustrated the positive results of the amnion usage in surgery of sciatic nerve neurotization in rabbits; a safety and effectiveness of this method have been also presented. The amniotic sac is a promising biomaterial for the prevention of pathological scarring and improvement of postoperative outcomes. However, further research and standardization of production are needed for its widespread use.

Keywords: venetoclax, relapsed or refractory B-cell lymphomas, survival, complete remission

For citation: Tsymbal IV, Semenov MS, Brunchukov VA, Dubova EA, Stepanyan GG, Lepsveridze LT, Lischuk SV, Astrelina T.A., Kobzeva I.V., Suchkova Yu.B., Serova O.F., Samoilov A.S., Parinov O.V.The Usage of an Amniotic Membrane to Minimize Pathological Scarring in Nerve Neurotization Surgery A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin. 2024.4:34-39. (In Russian) DOI: 10.33266/2782-6430-2024-4-34-39

 

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Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 13.09.2024. Accepted for publication: 11.10.2024

© 2025 Scientific journal - "Clinical Bulletin of the FMBС im. A.I. Burnasyan"
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