A.I. BURNASYAN FMBC CLINICAL BULLETIN

ISSN 2782-6430 (print)

State Research Center −Burnasyan Federal Medical Biophysical
Center of Federal Medical Biological Agency

The journal is published in Russian.
Format – A4.
The periodicity of the journal is 4 times a year.

Issue №2 2025 год

A.I. Burnasyan  FMBC clinical bulletin. 2023 № 4

E.A.Dubova, K.A.Pavlov

Grossing and Reporting of Pancreatic Ductal Adenocarcinoma Specimens after the Neoadjuvant Therapy

International Office, State Research Center – Burnasyan Federal Medical Biophysical Center

Contact person: Dubova Elena: dubovaea@gmail.com

Abstract
Pancreatic ductal adenocarcinoma is an aggressive tumor with poor prognosis and survival. Surgery is a treatment of choice for this tumors. Potentially resectable tumors are now treated with neoadjuvant therapy. This leads to necessity for pathologist to score the tumor response to neoadjuvant therapy. To date the international agreement guides for pathologic assessment of pancreatectomy specimens after neoadjuvant therapy are lack. Here we review the data on grossing and microscopic study of pancreatic ductal adenocarcinoma after neoadjuvant therapy, as well as data regarding the prognostic significance of tumor staging, therapy response and other pathologic parameters.

Keywords: pancreas, ductal adenocarcinoma, neoadjuvant therapy, tumor regress

For citation: Dubova EA, Pavlov KA. Grossing and Reporting of Pancreatic Ductal Adenocarcinoma Specimens After the Neoadjuvant Therapy. A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin. 2023;4:19-25 (In Russian). DOI: 10.33266/2782-6430-2023-4-4-19-25 (In Russian). DOI: 10.33266/2782-6430-2023-4-4-19-25

 

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Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Dubova E.A. – analysis of literature data, writing the text of the article
Pavlov K.A. –  text editing, approval of the final version of the manuscript text
Article received: 29.11.2023.  Accepted for publication: 15.12.2023

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