A.I. BURNASYAN FMBC CLINICAL BULLETIN

ISSN 2782-6430 (print)

State Research Center −Burnasyan Federal Medical Biophysical
Center of Federal Medical Biological Agency

The journal is published in Russian.
Format – A4.
The periodicity of the journal is 4 times a year.

Issue №3 2025 год

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A.I. Burnasyan  FMBC clinical bulletin. 2025 № 3

K.I. Medvedev, A.A. Zavialov

Laser Doppler Flowmetry in Assessing the State of the Microcirculatory
System in Patients with Cancer

International Office, State Research Center – Burnasyan Federal Medical Biophysical Center
of Federal Medical Biological Agency, Moscow, Russiа

Contact person: Medvedev Kirill Igorevich: kirillme11@yandex.ru

Abstract
Violation of microcirculation in body tissues can lead to various diseases. During the surgical treatment of patients with cancer, some of the blood vessels that supply the skin and other organs may be affected. To improve wound healing and prevent complications, it is important to maintain and enhance blood flow to damaged tissues.

Laser Doppler flowmetry (LDF) is a non-invasive technique that plays a crucial role in assessing the microcirculation of patients with cancer. It is easy to use and provides valuable information about the condition of blood flow in tissues.

LDF has helped to obtain crucial information for studying the principles of microvascular function and dysfunction. This method is based on measuring the change in blood flow velocity in a specific volume of tissue over a given time period. During the study, tissue is irradiated with laser light, and the reflected signal is recorded. The Doppler frequency shift that occurs when light interacts with moving red blood cells is then analyzed.

LDF can be useful for timely identifying the causes of complications during reconstructive plastic surgery, predicting the development of acute skin reactions during radiation therapy, and monitoring the success of various anastomosis procedures in the postoperative period.

Keywords: microcirculation, laser doppler flowmetry, oncology, malignant neoplasms

For citation: Medvedev K.I., Zavialov A. A. Functional Disorders after Mastectomy. Methods for Their Correction. A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin. 2025.3:62-66. (In Russian) DOI: 10.33266/2782-6430-2025-3-62-66

 

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Conflict of interest. The authors declare no conflict of interest. 
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors. 
Article received: 13.03.2025. Accepted for publication: 05.04.2025

© 2025 Scientific journal - "Clinical Bulletin of the FMBС im. A.I. Burnasyan"
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