A.I. Burnasyan FMBC clinical bulletin. 2026 № 1
A.V. Nikulin1, A.I. Romanikhin2, E.G. Gandybina1, S.K. Gogoleva1, S.S. Karpina1, T.V. Khorobrykh1
Surgical Tactics for the Treatment of a Type-Associated Pleural Empyema
1I.M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia , Moscow, Russian Federation
2City Clinical Hospital named after I.V.Davydovsky of the Department of Health of the city of Moscow, Russian Federation
Contact person: Nikulin Andrey Vladimirovich: nikulin5642@gmail.com
Abstract
Purpose: according to literature data, mortality in pleural empyema reaches 28 %. Issues related to the treatment of pleural empyema are widely covered in the literature, but there are not many publications on the treatment of covid-associated pleural empyema. This article is devoted to the treatment of covid-associated pleural empyema.
Keywords: bronchopleural fistula, classification of pleural empyema, covid-associated pleural empyema, pleural empyema
For citation: Nikulin A.V., Romanikhin A.I., Gandybina E.G., Gogoleva S.K, Karpina S.S., Khorobrykh T.V. Surgical Tactics for the Treatment of a Type-Associated Pleural Empyema. A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin. 2026.1:58-62. (In Russian) DOI: 10.33266/2782-6430-2026-1-58-62
REFERENCES
- Nikulin A.V. Lecheniye Empiyemy Plevry, Oslozhnennoy Bronkhoplevral’nym Svishchom s Primeneniyem Fibrinovogo Kleya = Treatment of Pleural Empyema Complicated by Bronchopleural Fistula with the Use of Fibrin Glue. Candidate’s Thesis (Med.). Specialization 3.1.9. «Surgery». Moscow Publ., 2023. 148 p. (In Russ.).
- Das N.N., Lakhotia S., Verma A. Surgical Outcome of Empyema Thoracis Patients with Special Correlation to Pre-Operative Contrast-Enhanced Computerized Tomography (CECT) Thorax Morphometry. Indian Journal of Thoracic and Cardiovascular Surgery. 2021;37;2:164-174. https://doi.org/10.1007/s12055-020-01053-5
- Yarlagadda K., Mi K., Sendil S., et al. A 31-Year-Old Man with COVID-19-Associated Empyema and Lupus Anticoagulant. American Journal of Case Reports. 2020;21:1-5. https://doi.org/10.12659/AJCR.926623
- Shah S., Mandal P., Chamlagain R., et al. Bronchopleural Fistula and Bilateral Pneumothorax in a Patient with COVID‐19. Clinical Case Reports. 2021;9;11:1-3. https://doi.org/10.1002/ccr3.5149
- Ayad S., Gergis K., Elkattawy S., et al. Loculated Empyema and SARS-CoV-2 Infection: a Report of Two Cases and Review of the Literature. European Journal of Case Reports in Internal Medicine. 2021:14. https://doi.org/10.12890/2021_002706
- Silalahi T.D.A., Suwita C. S. Culture-Negative Pleural Empyema after Coronavirus Disease-19 Resolution – a Case Report. Respiratory Medicine Case Reports. 2021;34:1-3. https://doi.org/10.1016/j.rmcr.2021.101473
- Placik D.A., Taylor W.L., Wnuk N.M. Bronchopleural Fistula Development in the Setting of Novel Therapies for Acute Respiratory Distress Syndrome in SARS-CoV-2 Pneumonia. Radiology Case Reports. 2020;15;11:2378-2381. https://doi.org/10.1016/j.radcr.2020.09.026
- Kamath S.D., Sharma B., Laik J. K., et al. Case Report of a Saga of Post-COVID-19 Complications. Cureus. 2021:1-10. https://doi.org/10.7759/cureus.16247
- Abbasi R., Javanmardi F.S., Mokhtari A., et al. Management of Pleural Empyema in a 12-Year-Old Obese Patient with COVID-19: a Pediatric Case Report. BMC Pediatrics. 2021;21;1:531. https://doi.org/10.1186/s12887-021-03007-1
- Divisi D., Zaccagna G., Angeletti C., et al. Pleural Empyema Associated with Alveolar‐Pleural Fistulas in Severe Acute Respiratory Syndrome Coronavirus 2. Clinical Case Reports. 2021;9;6:1-7. https://doi.org/10.1002/ccr3.4262
- Tessitore A., Patella M., Giuliani M., et al. Surgical Treatment of Pleural Empyema in Coronavirus Disease 19 Patients: the Southern Switzerland Experience. Interactive CardioVascular and Thoracic Surgery. 2021;32;3:367-370. https://doi.org/10.1093/icvts/ivaa269
- Chang S.H., Chen D., Paone D., et al. Thoracic Surgery Outcomes for Patients with Coronavirus Disease 2019 // The Journal of Thoracic and Cardiovascular Surgery. 2021;162;6:1655-1664. https://doi.org/10.1016/j.jtcvs.2021.01.069
- Crudeli C., Zilberman B., Williams J., et al. COVID-19’s Impact on Lung Tissue: a Case Report. International Journal of Surgery Case Reports. 2022;92:106905. https://doi.org/10.1016/j.ijscr.2022.106905
- Kutergin A.V., Shvetsov I.V., Borshchev S.V., et al. Complex Surgical Treatment of Nonspecific Acute Empyema of the Pleura with Bronchopleural Fistulas. Meditsinskaya Nauka i Obrazovaniye Urala = Medical Science and Education of the Urals. 2008;9;3:19-20 (In Russ.).
- Korymasov E.A. National Clinical Guidelines “Empyema of the Pleura”. Klinicheskiye Rekomendatsii = Clin. Recommendations. 2017;147004;1905:1-21 (In Russ.).
- Barskiy B.G., Gestkov K.G., Kosachenko V.M., et al. Single-Port Thoracoscopic Programmed Sanitation and Mini Thoracostomy with Vacuum Therapy in the Treatment of Pleural Empyema. Vysokotekhnologicheskaya Meditsina = High-tech Medicine. 2015;2;3:30-39 (In Russ.). http://doi.org/10.1089/lap.2019.0637
- Yasnogorodskiy O.O., Shulutko A.M., Pinchuk T.P., et al. Evolution of Methods of Complex Treatment of Patients with Nonspecific Pleural Empyema. Khirurgiya. Zhurnal im. N.I.Pirogova = Surgery. Journal named after NI Pirogov. 2017;4:24-29 (In Russ.). http://doi.org/10.17116/hirurgia2017424-29
- Light R.W. A New Classification of Parapneumonic Effusions and Empyema. Chest. 1995;108;2:299-301. https://doi.org/10.1378/chest.108.2.299
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 29.11.2025. Accepted for publication: 27.12.2025