A.I. BURNASYAN FMBC CLINICAL BULLETIN

ISSN 2782-6430 (print)

State Research Center −Burnasyan Federal Medical Biophysical
Center of Federal Medical Biological Agency

The journal is published in Russian.
Format – A4.
The periodicity of the journal is 4 times a year.

Issue №1, 2026

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A.I. Burnasyan  FMBC clinical bulletin. 2025 № 4

 

A.M. Kovalchuk1,2, A.A. Makhonko1,3, O.S. Orlova1

Combining Photoacoustic Imaging and Ultrasound Technologies
Has Significant Clinical Potential: a Review

1Pirogov Russian National Research Medical University, Moscow, Russia

2Federal Center for Brain and Neurotechnology FMBA of Russia, Moscow, Russia

3Frumkin Institute of physical chemistry and electrochemistry, Moscow, Russia

Contact person: Kovalchuk Anna Mikhaylovna: kleshchevvva.anna@mail.ru

 

Abstract
Photoacoustic imaging (PAI) enables the non-invasive acquisition of high-contrast images of deep tissues by detecting optical absorption from endogenous chromo-phores or exogenous agents and their subsequent ultrasound wave generation. This method holds significant clinical promise, particularly when combined with ultrason-ic techniques. This review examines the advantages of combined PAI/ultrasound (PAI/UST) systems for precise diagnostics and therapy monitoring in fields such as oncology, neurology, and wound healing. The integration of PAI and UST provides clinically relevant, multi-parametric information that enhances diagnostic capabili-ties.

Keywords: photoacoustic imaging, ultrasound diagnostics

For citation: Kovalchuk AM, Makhonko AA, Orlova OS. Combining Photoacoustic Imaging and Ultrasound Technologies Has Significant Clinical Potential: a Review. A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin. 2025.4:75-78. (In Russian) DOI: 10.33266/2782-6430-2025-4-75-78

 

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Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 25.10.2025. Accepted for publication: 20.11.2025

© 2026 Scientific journal - "Clinical Bulletin of the FMBС im. A.I. Burnasyan"
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