A.I. BURNASYAN FMBC CLINICAL BULLETIN

ISSN 2782-6430 (print)

State Research Center −Burnasyan Federal Medical Biophysical
Center of Federal Medical Biological Agency

The journal is published in Russian.
Format – A4.
The periodicity of the journal is 4 times a year.

Issue №1, 2026

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A.I. Burnasyan  FMBC clinical bulletin. 2026 № 1

S.Yu. Kaushanskaya, T.Yu. Sinitsyna

Radiation Cystitis as Complication In the Treatment of Patients
with Pelvic Oncopathology. Literary Review

International Office, State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russiа

Contact person: Kaushanskaya Svetlana Yuryevna: kaushanskay78@mail.ru

 

Abstract
Purpose: to analyze contemporary literature data on radiation cystitis as a complication of radiation therapy in patients with oncopathology, encompassing epidemiology, pathogenesis, diagnosis, treatment, and prevention.
Material and methods: a systematic review of publications from 2010 – 2025 was conducted, utilizing PubMed, Scopus, and eLibrary.ru databases. Eighteen key sources were selected, with emphasis on studies from 2023 – 2025. The analysis focuses on clinical, experimental, and review articles.
Results: radiation cystitis develops in 5 – 10 % of patients following pelvic radiation therapy, with peak incidence at 1 – 2 years. Pathogenesis involves endothelial dysfunction and fibrosis. Diagnosis combines cystoscopy and MRI. Hyperbaric oxygen therapy (success rate 80 – 90 %) and endoscopic coagulation are effective. Prevention incorporates modern radiation techniques.
Field of application: recommendations for oncological urologists in managing complications.
Conclusions: early detection and multidisciplinary approach mitigate radiation cystitis severity; further randomized trials are warranted.

Keywords: radiation cystitis, oncology, radiation therapy complications, treatment, prevention

For citation: Kaushanskaya SYu, Sinitsyna TYu. Radiation Cystitis as Complication In the Treatment of Patients with Pelvic Oncopathology. Literary Review. A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin. 2026.1:54-57. (In Russian) DOI: 10.33266/2782-6430-2026-1-54-57

 

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Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 23.11.2025. Accepted for publication: 25.12.2025

© 2026 Scientific journal - "Clinical Bulletin of the FMBС im. A.I. Burnasyan"
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