A.I. BURNASYAN FMBC CLINICAL BULLETIN

ISSN 2782-6430 (print)

State Research Center −Burnasyan Federal Medical Biophysical
Center of Federal Medical Biological Agency

The journal is published in Russian.
Format – A4.
The periodicity of the journal is 4 times a year.

Issue №1, 2026

more

A.I. Burnasyan  FMBC clinical bulletin. 2026 № 1

N.V. Rylova, O.V. Parinov

Therapeutic Strategies for Correcting Desynchronosis

International Office, State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russiа

Contact person: Rylova Natal’ya Victorovna: rilovanv@mail.ru

 

Abstract
Transmeridional movement and the corresponding change in time zone are accompanied by a syndrome of desynchronosis. Acute desynchronosis manifests itself in the form of pronounced disturbances in the sleep-wake rhythm and vegetative-vascular changes. This can lead to temporary inability to work effectively in the new environment. Similarly, moving to an area with an unfamiliar climate can also lead to the development of adaptive reactions that reduce functional capabilities. There are several treatment strategies that can help reduce the effects of jet lag on the normal circadian cycle.

Keywords: jet lag, melatonin, circadian rhythm

For citation: Rylova NV., Parinov OV. Therapeutic Strategies for Correcting Desynchronosis. A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin. 2026.1:85-88. (In Russian) DOI: 10.33266/2782-6430-2026-1-85-88

 

REFERENCES

  1. Никулин А.В. Лечение эмпиемы плевры, осложненной бронхоплевральным свищом с применением фибринового клея: Дис. … канд. мед. наук. М.: Первый МГМУ им. И.М.Сеченова Минздрава России (Сеченовский университет), 2023. 148 с. [Nikulin A.V. Lecheniye Empiyemy Plevry, Oslozhnennoy Bronkhoplevral’nym Svishchom s Primeneniyem Fibrinovogo Kleya = Treatment of Pleural Empyema Complicated by Bronchopleural Fistula with the Use of Fibrin Glue. Candidate’s Thesis (Med.). Moscow, Pervyy MGMU im. I.M.Sechenova Minzdrava Rossii (Sechenovskiy Universitet) Publ., 2023. 148 p. (In Russ.)].
  2. Das N.N., Lakhotia S., Verma A. Surgical Outcome of Empyema Thoracis Patients with Special Correlation to Pre-Operative Contrast-Enhanced Computerized Tomography (CECT) Thorax Morphometry. Indian Journal of Thoracic and Cardiovascular Surgery. 2021;37;2:164-174. Doi: 10.1007/s12055-020-01053-5.
  3. Yarlagadda K., Mi K., Sendil S., et al. A 31-Year-Old Man with COVID-19-Associated Empyema and Lupus Anticoagulant. American Journal of Case Reports. 2020;21:1-5. Doi: 10.12659/AJCR.926623
  4. Shah S., Mandal P., Chamlagain R., et al. Bronchopleural Fistula and Bilateral Pneumothorax in a Patient with COVID-19. Clinical Case Reports. 2021;9;11:1-3. Doi: 10.1002/ccr3.5149
  5. Ayad S., Gergis K., Elkattawy S., et al. Loculated Empyema and SARS-CoV-2 Infection: a Report of Two Cases and Review of the Literature. European Journal of Case Reports in Internal Medicine. 2021:14. Doi: 10.12890/2021_002706.
  6. Silalahi T.D.A., Suwita C. S. Culture-Negative Pleural Empyema after Coronavirus Disease-19 Resolution – a Case Report. Respiratory Medicine Case Reports. 2021;34:1-3. Doi: 10.1016/j.rmcr.2021.101473
  7. Placik D.A., Taylor W.L., Wnuk N.M. Bronchopleural Fistula Development in the Setting of Novel Therapies for Acute Respiratory Distress Syndrome in SARS-CoV-2 Pneumonia. Radiology Case Reports. 2020;15;11:2378-2381. Doi: 10.1016/j.radcr.2020.09.026.
  8. Kamath S.D., Sharma B., Laik J. K., et al. Case Report of a Saga of Post-COVID-19 Complications. Cureus. 2021:1-10. Doi: 10.7759/cureus.16247.
  9. Abbasi R., Javanmardi F.S., Mokhtari A., et al. Management of Pleural Empyema in a 12-Year-Old Obese Patient with COVID-19: a Pediatric Case Report. BMC Pediatrics. 2021;21;1:531. Doi: 10.1186/s12887-021-03007-1.
  10. Divisi D., Zaccagna G., Angeletti C., et al. Pleural Empyema Associated with Alveolar-Pleural Fistulas in Severe Acute Respiratory Syndrome Coronavirus 2. Clinical Case Reports. 2021;9;6:1-7. Doi: 10.1002/ccr3.4262.
  11. Tessitore A., Patella M., Giuliani M., et al. Surgical Treatment of Pleural Empyema in Coronavirus Disease 19 Patients: the Southern Switzerland Experience. Interactive CardioVascular and Thoracic Surgery. 2021;32;3:367-370. Doi: 10.1093/icvts/ivaa269.
  12. Chang S.H., Chen D., Paone D., et al. Thoracic Surgery Outcomes for Patients with Coronavirus Disease 2019. The Journal of Thoracic and Cardiovascular Surgery. 2021;162;6:1655-1664. Doi: 10.1016/j.jtcvs.2021.01.069.
  13. Crudeli C., Zilberman B., Williams J., et al. COVID-19’s Impact on Lung Tissue: a Case Report. International Journal of Surgery Case Reports. 2022;92:106905. Doi: 10.1016/j.ijscr.2022.106905.
  14. Кутергин А.В., Швецов И.В., Борщев С.В. и др. Комплексное хирургическое лечение неспецифической острой эмпиемы плевры с бронхоплевральными свищами // Медицинская наука и образование Урала. Т.9. №.3. С. 19-20 [Kutergin A.V., Shvetsov I.V., Borshchev S.V., et al. Complex Surgical Treatment of Nonspecific Acute Empyema of the Pleura with Bronchopleural Fistulas. Meditsinskaya Nauka i Obrazovaniye Urala = Medical Science and Education of the Urals. 2008;9;3:19-20 (In Russ.)].
  15. Корымасов Е.А. Национальные клинические рекомендации «Эмпиема плевры» // Клин. рекомендации. Т.147004. №1905. С. 1-21 [Korymasov E.A. National Clinical Guidelines “Empyema of the Pleura”. Klinicheskiye Rekomendatsii = Clinical Recommendations. 2017;147004;1905:1-21 (In Russ.)].
  16. Барский Б.Г., Жестков К.Г., Косаченко В.М. и др. Однопортовые торакоскопические программированные санации и миниторакостомия с вакуум-терапией в лечении эмпиемы плевры // Высокотехнологическая медицина. 2015. Т.2. №3. С. 30-39 [Barskiy B.G., Gestkov K.G., Kosachenko V.M., et al. Single-Port Thoracoscopic Programmed Sanitation and Mini Thoracostomy with Vacuum Therapy in the Treatment of Pleural Empyema. Vysokotekhnologicheskaya Meditsina = High-Tech Medicine. 2015;2;3:30-39 (In Russ.)]. Doi: 10.1089/lap.2019.0637.
  17. Ясногородский О.О., Шулутко А.М., Пинчук Т.П. и др. Эволюция методов комплексного лечения больных с неспецифической эмпиемой плевры // Хирургия. Журнал им. Н.И.Пирогова. 2017. №4. С. 24-29 [Yasnogorodskiy O.O., Shulutko A.M., Pinchuk T.P., et al. Evolution of Methods of Complex Treatment of Patients with Nonspecific Pleural Empyema. Khirurgiya. Zhurnal im. N.I.Pirogova = Surgery. Journal named after N.I.Pirogov. 2017;4:24-29 (In Russ.)]. Doi: 10.17116/hirurgia2017424-29.
  18. Light R.W. A New Classification of Parapneumonic Effusions and Empyema. Chest. 1995;108;2:299-301. Doi: 10.1378/chest.108.2.299

Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 23.11.2025. Accepted for publication: 25.12.2025

© 2026 Scientific journal - "Clinical Bulletin of the FMBС im. A.I. Burnasyan"
Scroll to Top