A.I. BURNASYAN FMBC CLINICAL BULLETIN

ISSN 2782-6430 (print)

State Research Center −Burnasyan Federal Medical Biophysical
Center of Federal Medical Biological Agency

The journal is published in Russian.
Format – A4.
The periodicity of the journal is 4 times a year.

Issue №1, 2026

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A.I. Burnasyan  FMBC clinical bulletin. 2026 № 1

M.N. Ziyatdinov, O.N. Prochorova, A.M. Mikhaylenko, I.L. Shafranskii, M.G. Archegova, A.R. Tukov

Incidence of Nontoxic single thyroid nodule among Liquidators of the consequences
Chernobyl Accident, Employees of enterprises and Organizations Served
by Healthcare Institutions of the FMBA of Russia

International Office, State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russiа

Contact person: Ziyatdinov Marat Nazifovich: zidik@yandex.ru

 

Abstract
Purpose: assessment of the incidence of nontoxic single thyroid nodule (ICD 10; E04.1) among liquidators of the consequences of the Chernobyl accident, employees of enterprises and organizations served by healthcare institutions of the Federal Medical and Biological Agency of Russia.
Material and methods: in the study uses the information base of the Industry Register of Persons Exposed to Radiation as a Result of the Chernobyl Accident (IRR), developed by the State Research Center − Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency and containing information on newly diagnosed thyroid diseases – nontoxic single thyroid nodule (ICD 10; E04.1). The registry database contains information on 485 diagnoses of nontoxic single thyroid nodule (ICD 10; E04.1), diagnosed for the first time, men – 388 (80.0 %), women – 97 (20.0 %), liquidators of the consequences of the Chernobyl accident, employees of enterprises and organizations served by healthcare institutions of the Federal Medical and Biological Agency of Russia.
The statistical software package Excel was used to process the research results. Original programs were developed to calculate absolute and intensive indicators, the growth rate. The incidence of nontoxic single thyroid nodule (ICD 10; E04.1) was calculated per 1 000 workers.
Results: an assessment was made of the incidence of nontoxic single thyroid nodule (ICD 10; E04.1) among liquidators of the Chernobyl accident, employees of enterprises and organizations served by healthcare institutions of the Federal Medical and Biological Agency of Russia. The features of the structure of registered diseases of this contingent were established. An assessment was made of the dynamics of incidence for the period 1989-2023 for this nosology.
Conclusion: in the structure of newly diagnosed diseases of the endocrine system, nutritional disorders and metabolic disorders (ICD 10; E00-E90) among liquidators of the consequences of the Chernobyl accident, men, nontoxic single thyroid nodule (ICD 10; E04.1) occupies the fifth rank place – 5.8 %. Among women, the sixth rank place is the third rank place – 5.4 %.
The dynamics of the epidemiological process shows that this nosology affects workers of working age (the maximum incidence of men in the age group of 50-59 years was 1.4 ± 0.1; women – 40-49 years was 2.6 ± 0.5).
The aging of the contingent determined the negative growth rate both in men = -6.55 % and among women = -25.36 %.
The ratio of the incidence rate of men (1.2 ± 0.1) to women (1.7 ± 0.2) for 1989-2023, the Lenz-Bauer index, was 1.42, which indicates that this contingent of people lives in areas with iodine deficiency.
Based on the results of the study, the following recommendations are given developed: measures are needed to eliminate iodine deficiency in the diet of contingents of people served by healthcare institutions of the Federal Medical and Biological Agency of Russia.

Keywords: accident, Chernobyl Nuclear Power Plant, liquidators, morbidity, nontoxic single thyroid nodule, iodine deficiency

For citation: Ziyatdinov MN, Prochorova ON, Mikhaylenko AM, Archegova, MG, Tukov AR. Incidence of Nontoxic single thyroid nodule of Chernobyl Accident Liquidators, Employees of enterprises and Organizations Served by Healthcare Institutions of the FMBA of Russia. A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin. 2026.1:89-94. (In Russian) DOI: 10.33266/2782-6430-2026-1-89-94

 

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Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 29.11.2025. Accepted for publication: 27.12.2025

© 2026 Scientific journal - "Clinical Bulletin of the FMBС im. A.I. Burnasyan"
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