A.I. Burnasyan FMBC clinical bulletin. 2023 № 1
N.A. Pashchenko, I.S. Makhneva, E.V. Metelkina, S.P. Yarilkina, N.O. Grishkova
Specific Prevention of Inflammatory Complications in Users with Dentures on Dental Implants
A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: Pashchenko Natalya: natala.pashchenko2019@gmail.com
Abstract
Purpose: analysis of the preventive effectiveness of the agent based on bacteriophages “Phagodent” in persons with dental implants.
Material and methods: two groups were compared: with standard hygienic oral care and with additional applications of Phagodent gel on the gum (main group, 15 people, bridges on 49 implants; comparison group, 10 people, bridges on 42 implants); observation of patients with implants. For comparison, hygienic periodontal indices (oral hygiene index, hygiene index, gingivitis index, Mulleman index) were used.
Results: when using the Phagodent gel at home and with standard oral hygiene, no development of periimplantitis with bone resorption was recorded during the year of observation. At the same time, mucositis was found in one implant in the main group (2.0%) and in two in the comparison group (4.8%). A year later, the index of oral hygiene of IG-U deteriorated in the main group to 1.9±0.1, in the comparison group to 2.1± 0.2; the index of hygiene of IG in the comparison group corresponded to 1.3±0.3, in the main group – 1.0±0.1; the index of gingivitis of IG in the main group was 0.1± 0.1; in the control group 0.2 ±0.1; The Mulleman index in a year it did not exceed 0.1 ±0.1 in both groups. Thus, the use of “Phagodent” gel in the main group of patients prevented the development of mucositis due to the positive effect on oral hygiene, reflected by the hygienic indices of IGM-U and IGIM. Due to the positive effect on oral hygiene in patients with dentures on dental implants, the gel based on bacteriophages “Phagodent” has a preventive effect on inflammatory complications in the state of periimplant tissues and can be used by the patient independently at home.
Keywords: retinal vein occlusion, macular edema, neovascularizations
For citation: Pashchenko NA, Makhneva IS, Metelkina EV, Yarilkina SP, Grishkova NO. Specific Prevention of Inflammatory Complications in Users with Dentures on Dental Implants. A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin. 2023.1:24-26. (In Russian) DOI: 10.33266/2782-6430-2023-1-24-26
REFERENCES
- Kulakov A.A. Dentalnaya Implantatsiya = Dental Implantation. Moscow, GEOTAR-Media Publ., 2018. 400 p. (In Russ.).
- Ortopedicheskaya Stomatologiya = Orthopedic Dentistry. National Leadership. V.1. Ed. Lebedenko I.Yu., Arutyunov S.D., Ryakhovskiy A.N. Moscow, GEOTAR-Media Publ., 2022. 520 p. (In Russ.).
- Ortopedicheskaya Stomatologiya = Orthopedic Dentistry. National Leadership. V.2. Ed. Lebedenko I.Yu., Arutyunov S.D., Ryakhovskiy A.N. Moscow, GEOTAR-Media Publ., 2022. 416 p. (In Russ.).
- Kulakov A.A. Khirurgicheskaya Stomatologiya = Surgical Dentistry. Moscow, GEOTAR-Media Publ., 2021. 408 p. (In Russ.).
- Zurabov A.Yu., Karkishchenko N.N., Popov D.V., Zhilenkov Ye.L., Popova V.M. Creation of a Domestic Collection of Bacteriophages and Principles of Development of Therapeutic and Prophylactic Phage Preparations. Biomeditsina = Journal Biomed. 2012;1:132-138 (In Russ.).
- Nikitin V.V., Pashkova G.S., Karton Ye.A., Isadzhanyan K.Ye., Popova V.M. The Study of the Effectiveness of the Use of a Bacteriophage-Based Agent in the Complex Treatment of Gingivitis in Patients with Fixed Orthodontic Structures. Parodontologiya= Periodontology. 2014;3:42-49 (In Russ.).
- Drucker V.V., Gorshkova A.S. Bacteriophages and Their Functioning in the Biofilms. Izvestiya Irkutskogo Gosudarstvennogo Universiteta. Seriya “Biologiya. Ecologiya” = The Bulletin of Irkutsk State University. Series “Biology. Ecology”. 2012;3:8-16 (In Russ.).
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 11.11.2022. Accepted for publication: 30.09.2022