A.I. BURNASYAN FMBC CLINICAL BULLETIN

ISSN 2782-6430 (print)

State Research Center −Burnasyan Federal Medical Biophysical
Center of Federal Medical Biological Agency

The journal is published in Russian.
Format – A4.
The periodicity of the journal is 4 times a year.

Issue №1, 2026

A.I. Burnasyan  FMBC clinical bulletin. 2025 № 4

 

A.E. Krasnov1, Yu.D. Udalov1, E.N. Mingazova2,3,4

Comorbidity and Multimorbidity from the Point of Risk Assessment and Assistance
to Patients with Chronic Pathology at Infectious Risks

1International Office, State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russiа

2N.A. Semashko National Research Institute of Public Health

3Kazan State Medical University

4Russian Medical Academy of Continuous Professional Education

Contact person: Mingazova Elmira Nurislamovna: elmira_mingazova@mail.ru

 

Abstract
Background: The article examines the problem of comorbidity and multimorbidity from the perspective of health risks for patients, treatment outcomes and burden on the healthcare system. Particular attention is paid to the differences between these concepts, their prevalence among different population groups, as well as the role of comorbidity in aggravating the course of infectious diseases, including COVID-19. Key comorbidity clusters are analyzed in detail: cardiovascular, respiratory and oncological diseases, as well as their mutual influence. Modern methods of parametric comorbidity assessment, such as the Charlson index and the Elixhauser index, and their application in clinical practice are considered. Comorbidity management strategies are highlighted, including a multidisciplinary approach, personalized medicine and digital technologies. Particular emphasis is placed on global and regional features of the organization of medical care for patients with multiple chronic diseases, as well as on lessons learned during the COVID-19 pandemic.

Keywords: comorbidity, multimorbidity, chronic diseases, infectious diseases, COVID-19, personalized medicine, multidisciplinary approach, healthcare system

For citation: Krasnov AE, Udalov YuD, Mingazova EN. Comorbidity and Multimorbidity from the Point of Risk Assessment and Assistance to Patients with Chronic Pathology at Infectious Risks. A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin. 2025.4:90-95. (In Russian) DOI: 10.33266/2782-6430-2025-4-90-95

 

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Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 08.07.2025. Accepted for publication: 13.08.2025

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